Saez-Rodriguez Group

Systems biomedicine

Bence Szalai

I graduated in 2008 as medical doctor at Semmelweis University, Budapest, Hungary. During my university studies I joined the laboratory of Professor Lászlo Hunyady as an undergraduate research student. After graduating I continued to work in the same lab as a PhD student. During my PhD years I investigated the dimerization of G-Protein Coupled Receptors using various biophysical methods (fluorescence/confocal microscopy, resonance energy transfer based methods). I received my PhD degree in 2016.
Since 2013 my interest shifted towards the field of computational biology, especially the using of machine learning methods in the analysis of large biological datasets and the modeling of cell signaling systems. In the last years I participated in the DREAM Challenges collaborative competitions, where I built models to predict the smell of odorant molecules based on molecular structure and to predict the synergistic effects of different drug combinations in tumor cell lines.
I am a post-doc at the group of Professor Julio Saez-Rodriguez in the Joint Research Center for Computational Biomedicine in Aachen since 2017 January. I am working on the PrECISE EU project, which aims to improve patient risk-stratification and treatment in prostate cancer by developing new computational approaches to exploit next generation molecular data.

Tel: +44 (0) 1223 49 4576 / Fax: +44 (0) 1223 48 46 96

Research interests

My main research interests are the application of machine learning methods in the analysis of large-scale biological datasets, pharmacogenomics, drug-drug interactions and top-down/bottom-up modeling of biological signaling systems.

Professional career

2017-Present Post-doc, JRC-COMBINE, Aachen, Germany
2013 Assistant lecturer, Department of Physiology, Semmelweis University, Budapest, Hungary
2012-2016 Assistant research fellow, MTA-SE Laboratory of Molecular Physiology, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary
2011-2012 Assistant research fellow, Department of Physiology, Semmelweis University, Budapest, Hungary

Education

2008-2016 Ph.D. in molecular medicine; Semmelweis University, Budapest, Hungary
2002-2008 Doctor of medicine (M.D.); Semmelweis University, Budapest, Hungary