Modeling Cell-Cell Interactions from Spatial Molecular Data with Spatial Variance Component Analysis
Arnol D Cell reports, 2019
Signatures of cell death and proliferation in perturbation transcriptomics data—from confounding factor to effective prediction
Szalai.B Nucleic Acids Research, 2019
Transfer of regulatory knowledge from human to mouse for functional genomic analysis.
Holland CH Biochim Biophys Acta Gene Regul Mech, 2019
Reproducible biomedical benchmarking in the cloud: lessons from crowd-sourced data challenges.
Ellrott K Genome Biol, 2019
Assessment of network module identification across complex diseases.
Choobdar S Nat Methods, 2019
Novel plasma peptide markers involved in the pathology of CKD identified using mass spectrometric approach.
Gajjala PR J Mol Med (Berl), 2019
Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data.
Schäfer A Mol Syst Biol, 2019
Benchmark and integration of resources for the estimation of human transcription factor activities.
Garcia-Alonso L Genome Res, 2019
Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer.
Tang J NPJ Syst Biol Appl, 2019
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.
Menden MP Nat Commun, 2019
Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening.
Picco G Nat Commun, 2019
Analysis of the Human Kinome and Phosphatome by Mass Cytometry Reveals Overexpression-Induced Effects on Cancer-Related Signaling.
Lun XK Mol Cell, 2019
Author Correction: Linking drug target and pathway activation for effective therapy using multi-task learning.
Yang M Sci Rep, 2019
MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance.
Sale MJ Nat Commun, 2019
MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis.
Kotelnikova E Proc Natl Acad Sci U S A, 2019
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Behan FM Nature, 2019
Elastin imaging enables noninvasive staging and treatment monitoring of kidney fibrosis.
Sun Q Sci Transl Med, 2019
Big science and big data in nephrology.
Saez-Rodriguez J Kidney Int, 2019
Multi-omic measurements of heterogeneity in HeLa cells across laboratories.
Liu Y Nat Biotechnol, 2019
From expression footprints to causal pathways: contextualizing large signaling networks with CARNIVAL
Liu A npj Systems Biology and Applications, 2019
The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury.
Späth MR Kidney Int, 2018
Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue.
Pellegrinelli V Nat Commun, 2018
Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury.
Souza T Front Genet, 2018
Computational discovery of dynamic cell line specific Boolean networks from multiplex time-course data.
Razzaq M PLoS Comput Biol, 2018
The germline genetic component of drug sensitivity in cancer cell lines.
Menden MP Nat Commun, 2018