Saez-Rodriguez Group

Systems Biomedicine

Christoph Mahler

I gained my medical degree at LMU Munich, where I joined the group of Martin Kerschensteiner at the Institute of Clinical Neuroimmunology. In cooperation with Thomas Misgeld, I applied 2-photon in-vivo imaging to track axonal calcium dynamics in an animal model of multiple sclerosis. I started clinical training in neurology and collaborated with the Institute of Nuclear Medicine to establish TSPO-PET imaging of neuroinflammatory dynamics. I continued internal medicine training at the West London Renal and Transplant Centre, where my interest in kidney transplantation at the intersection between medicine and immunology was sparked. Currently, I am supported by the clinician scientist program Heidelberg, where my research is focused on improving outcomes for patients with end stage kidney disease through transplantation.

Research Interests

Physician scientist with a background in immunology and nephrology. My research focuses on regulatory B-cells, the development of tolerance inducing therapies for kidney transplant recipients, and the prediction of kidney graft survival through electronic health records and deep phenotyping.

Professional Career

2024-present Clinician Scientist Program, Medical Faculty, Universität Heidelberg; Advisor: Julio Saez-Rodriguez
2020-2024 Residency (Internal medicine and Nephrology), University Hospital, Universität Heidelberg
2019-2020 Internal medicine training, Imperial College Healthcare NHS Trust, London, United Kingdom
2018 Residency (Neurology), University Hospital, Ludwig-Maximilians-Universität München, Germany

Education

2018 Dr. med., (Medicine), Ludwig-Maximilians-Universität München, Germany; Thesis Title: Mechanisms of axonal calcium dynamics in an animal model of multiple sclerosis; Advisor: Martin Kerschensteiner