Saez-Rodriguez Group

Systems Biomedicine

Lorna Wessels

In my Bachelor studies I received extensive training in wet-lab molecular biotechnology as well as first insights into computational biology. During my master’s I took a deep dive into computational biology and bioinformatics focusing on the integration of different modalities of single-cell sequencing data. For my master thesis in the lab of Julio Saez-Rodriguez I constructed a resource for marker transcription factors across cell types and tissues as a reference in the context of gene regulatory network evaluation. In 2022, I started my PhD in the group of Mahak Singhal at the European Center for Angioscience where I will mainly focus on developing methods to uncover regulatory processes underlying the vascular circadian rhythms.

Research Interests

I am particularly interested in how we can computationally model the complex regulatory processes orchestrating gene expression in health and disease by integrating different omics data. Further, I am eager to find ways to translate the common effort of the scientific community into valuable resources in order to refine and evaluate gene regulatory networks in a variety of contexts.

Professional Career

2022 - current PhD with Dr. Mahak Singhal at the European Center for Angioscience, Medical Faculty Mannheim, co-supervised by Julio Saez-Rodriguez
2021 - 2022 Master Thesis at the Institute for Computational Biomedicine, Heidelberg University Hospital
2018 - 2022 Research Internships at the German Cancer Research Center, the Women’s Hospital and the Institute of Pathology in Heidelberg
2014 - 2018 Student trainee at Heidelberg Instruments Mikrotechnik GmbH, Heidelberg, Germany


2018 - 2022 Molecular Biotechnology, MSc., Universität Heidelberg, Germany
2014 - 2018 Molecular Biotechnology, BSc., Universität Heidelberg, Germany