Saez-Rodriguez Group

Systems Biomedicine

Macabe Daley

My relatively short but varied career so far (read: weird but wonderful), has been driven by a desire to play some kind of role in improving cancer care, even though the exact role that I envisioned has had some iterations along the way.

Driven by an interest in innovation and intellectual property, in 2015 I started a dual degree in Biomedical Science and Law, in Australia. Realising Law wasn´t for me, I became interested in the commercial side of life sciences. But some time later, after some stints in a business development role and two biopharmaceutical manufacturing companies, I became much more interested in being a part of the research itself. Not one to love lab work however, I stumbled into the AI/ML field and began to gain skills and programming experience along the way through electives and summer internships.

After graduating in 2020, I was fortunate to join the Children’s Cancer Institute as a Bioinformatics RA, within the Computational Biology team and Dr Mark Pinese’s Genomic Childhood Cancer risk team. Over the course of 2.5 years, I worked as part of a multi-disciplinerary clinical team to develop and maintain the pipeline for a clinical study on childhood cancer predisposition using whole-genome sequencing trio data.

Then in 2023, I moved to Europe and started an online Masters in Biomedical Data Science offered by a consortium of Spanish universities and led by Universitat Rovira i Virgil. Most recently in June 2024, I joined DKFZ and the Saez-Rodriguez lab on a part-time basis as a Data Scientist, where I am excited to be primarily working in the SMART-CARE consortium to analyse metabolomics and proteomics data in the context of cancer relapse.

Research Interests

Cancer research holds a special place in my heart, and I am especially passionate about understanding the mechanisms behind its development, progression, and relapse. My research interests within the scope of this is varied, because there is so much biology we do not yet understand and many promising areas of research. However particular areas of interest to me revolve around quantifying risk of occurrence and relapse, whether this be prediction, stratification or treatment efficacy, and I am also interested in survival analysis and spatial omics. My previous research experience includes machine learning, cancer predisposition, clinical genetics, and computational pipeline development. Ultimately, contributing to research that can translate into meaningful outcomes to patients means a lot to me, and being a part of a team working on this is very motivating.

Professional Career

2021-2023 Bioinformatics Research Assistant, Children's Cancer Institute, Sydney, Australia.
2020 Associate Project Manager, Luina Bio, Brisbane, Australia.
2021-2023 Bioinformatics Research Assistant, Children's Cancer Institute, Sydney, Australia.
2020 Associate Project Manager, Luina Bio, Brisbane, Australia.
2019 Summer Research, Centre for Accident Research and Road Safety, QUT, Australia.
2018 Summer Research, Institute of Health and Biomedical Innovation, QUT, Australia.
2018 Quality Control Intern, Patheon (Thermo Fisher Scientific), Brisbane, Australia.
2018 Summer Research, Centre for Accident Research and Road Safety, QUT, Australia.
2018 Summer Research, Institute of Health and Biomedical Innovation, QUT, Australia.
2018 Quality Control Intern, Patheon (Thermo Fisher Scientific), Brisbane, Australia.

Education

2023-present MSc in Biomedical Data Science
2015-2020 BBiomedSc & LLB(Hons)