Marc-Antoine Jacques

Biography

I have a mixed background in biotechnology (Engineering degree, 2013-2016, ESBS, Strasbourg), biophysics (Msc, 2015-2016, University of Strasbourg), and bioinformatics (Msc, 2016-2018, University of Bern). For my PhD (2018–2022), I worked in the lab of Olivier Pertz at the University of Bern. There, I developed computational techniques to study signalling dynamics in individual cells using live microscopy. My work contributed to new insights into cancer, signalling networks, epithelium homeostasis, and the prediction of cellular perturbations. I then joined the lab of John Marioni at the University of Cambridge and EMBL-EBI (2022–2025) as an EMBO postdoctoral fellow, where I developed methods to compare and predict single-cell transcriptomics atlases across species, with a focus on early embryo development.

Research Interests

In October 2025, I joined the Saez lab for a second postdoc, in collaboration with GSK, to study fibrosis across multiple organs. I plan to leverage my background in dynamical biological systems and my expertise in single-cell analysis to build a multi-scale picture of how fibrosis develops. By integrating diverse data modalities, I aim to identify both organ-specific and common mechanisms underlying fibrosis, with the ultimate goal of translating these insights into new therapeutic strategies.

Professional Career

Education

Contact Information