I first enrolled in the Biology Department of Hacettepe University, followed by joining the Masters program in the Molecular Biology and Genetics Department of Bogazici University. The aim was to identify novel genes/mutations in neurodegenerative disorders using whole genome and exome sequencing methods.
In 2020, I finished my PhD in Computational Biology at EMBL, Heidelberg, which was followed by a short postdoctoral position. During my time at EMBL, I gained a lot of experience in both experimental and computational methods. For example, I developed a microbiome-based kit for colorectal cancer screening. I also analysed shotgun metagenomics and 16S rRNA sequencing data of different human microbiomes including gut, saliva and tissue. Computationally, I established different machine learning models for early detection of different diseases such as colon and pancreas cancers. In 2021, I joined the Saez-Rodriguez Lab at Heidelberg University Institute of Computational Biomedicine. I am currently working on unraveling the complex interactions between the host and microbiome at different levels in order to understand the underlying mechanisms of these interactions and translate this knowledge to the diagnostic and/ or therapeutic field.
I have a strong interest in medical and environmental microbiome research. I aim to integrate microbial information with other omics layers to have a broader understanding of complex disease mechanisms such as cancer, heart failure and skin diseases. My goal is to maximise usage of microbiome data and build multidimensional models. I am keen to unravel the complex interactions between the host and microbiome at different levels. I would like to understand the underlying mechanisms and translate this knowledge to the diagnostic and/ or therapeutic field by using the multi-omics data analysis approaches. Currently, I focus on host and microbiome interactions in lung cancer (PROMISE Consortium), heart failure and skin diseases (such as psoriasis, atopic dermatitis and rheumatoid arthritis).
|2021-present||Postdoctoral researcher – Institute for Computational Biomedicine, Heidelberg University, Germany|
|2020-2021||Postdoctoral researcher – European Molecular Biology Laboratory (EMBL), Heidelberg|
|2015-2015||Visiting Scientist – European Molecular Biology Laboratory (EMBL), Heidelberg|
|2016-2020||PhD in Computational Biology – European Molecular Biology Laboratory (EMBL), Heidelberg|
|2012-2015||Masters of Science in Molecular Biology and Genetics – Bogazici University, Turkey|
|2007-2011||Bachelor of Science in Biology – Hacettepe University, Turkey|