Sebastian Lobentanzer
During my PhD training in pharmacology, I combined my biomedical knowledge base with information technology; starting out in Java, I have mainly worked in R and graph database systems, and recently have taken up Python. I am an advocate for reproducibility in the biomedical sciences and prefer to work with integrated workflows involving markdown (Rmarkdown, Jupyter Notebook, and Obsidian). Further, I am very much committed to professional illustration and typesetting, British English, and the Oxford comma.
ORCiD: https://orcid.org/0000-0003-3399-6695Research Interests
I am interested in the advancement of causal reasoning in interaction modelling at both the intra- and inter-cellular levels. A pharmacist by training, my focus lies on the complex dynamics of pathologic changes (transcription, translation, and protein interactions) and the molecular action of drugs. My aim is to integrate the informational wealth of modern omics data with the stern logic of causal reasoning, to address the issue of irreproducibility due to spurious correlation and to enable better predictions for the application of therapeutics. Focus points of my work will be overcoming the drug resistance of High-Grade Serous Ovarian Cancer (HGSOC) as part of the DECIDER EU project and integrating pharmacologic/toxicologic prior knowledge with omics data in the context of the TransQST project, both funded by the European Union (GA No. 965193 and No. 116030).
Professional Career
| 2021-present | Postdoctoral research fellow at Heidelberg University Clinic, Heidelberg, Germany |
| 2020-2021 | Postdoctoral research fellow at Goethe-University, Frankfurt, Germany and Hebrew University, Jerusalem, Israel |
| 2015-2020 | Research fellow and teaching assistant at Goethe-University, Frankfurt and Hebrew University, Jerusalem |
| 2014-present | Pharmacist (deputy head), Spessart-Apotheke, Bad Orb, Germany |
Education
| 2015-2020 PhD, Neuro-immune pharmacology, Goethe-University, Frankfurt, Germany | |
| 2008-2013 Pharmacy (Licensure), Goethe-University, Frankfurt, Germany | |
| 2004-2006 Audio engineer (Diploma), School of Audio Engineering, Frankfurt, Germany |