Saez-Rodriguez Group

1. How will artificial intelligence and bioinformatics change our understanding of IgA in the next decade?

Büllow, Dimitrov, et al. Seminars in Immunopathology, 2021

2. Integrated intra- and intercellular signaling knowledge for multicellular omics analysis

Turei Molecular Systems Biology, 2021

3. PHONEMeS: Efficient Modeling of Signaling Networks Derived from Large-Scale Mass Spectrometry Data

Gjerga et al. J Prot Research, 2021

4. Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses

Dugourd A Molecular Systems Biology, 2021

5. Norepinephrine promotes triglyceride storage in macrophages via beta2‐adrenergic receptor activation

Petkevicius et al FASEB Journal, 2021

6. Differential expression of microRNA miR-150-5p in IgA nephropathy as a potential mediator and marker of disease progression

Pawluczyk et al. Kidney Int, 2021

7. Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ

Cappelletti Cell, 2020

8. Experimental and computational technologies to dissect the kidney at the single-cell level

Kuppe, Perales-Paton Nephrol Dial Transplant, 2020

9. A statistical framework for assessing pharmacological response and biomarkers using uncertainty estimates

Wang et al. eLife, 2020

10. Why do pathway methods work better than they should?

Szalai FEBS letters, 2020

11. Decoding myofibroblast origins in human kidney fibrosis

Kuppe Nature, 2020

12. Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis

Mohs J Hepatology, 2020

13. The tissue proteome in the multi-omic landscape of kidney disease

Rinschen Nature Rev Nephrology, 2020

14. Gene selection for optimal prediction of cell position in tissues from single-cell transcriptomics data

Tanevski J Life Science Alliance, 2020

15. Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease

Sellmayr J Am Soc Nephrol, 2020

16. Inferring clonal composition from multiple tumor biopsies

Manica npj sys bio , 2020

17. BIAS: Transparent reporting of biomedical image analysis challenges

Maier-Hein Med Image Anal, 2020

18. Big Data Approaches in Heart Failure Research

Lanzer Current Heart Failure Reports, 2020

19. The Global Phosphorylation Landscape of SARS-CoV-2 Infection

Bouhaddou Cell, 2020

20. Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN

Gleitz H Blood, 2020

21. Community Assessment of the predictability of cancer protein and phosphoprotein levels from genomics and transcriptomics

Yang M Cell Systems, 2020

22. The Minimum Information about a Molecular Interaction Causal Statement (MI2CAST)

Touré V Bioinformatics, 2020

23. Converting networks to predictive logic models from perturbation signalling data with CellNOpt

Gjerga E Bioinformatics, 2020

24. Stratification and prediction of drug synergy based on target functional similarity

Yang M npj Systems Biology and Applications, 2020

25. Consensus Transcriptional Landscape of Human End‐Stage Heart Failure

Ramirez-Flores, Lanzer JAHA, 2020