Saez-Rodriguez Group

1. Norepinephrine promotes triglyceride storage in macrophages via beta2‐adrenergic receptor activation

Petkevicius et al FASEB Journal, 2021

2. Differential expression of microRNA miR-150-5p in IgA nephropathy as a potential mediator and marker of disease progression

Pawluczyk et al. Kidney Int, 2021

3. Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ

Cappelletti Cell, 2020

4. Experimental and computational technologies to dissect the kidney at the single-cell level

Kuppe, Perales-Paton Nephrol Dial Transplant, 2020

5. A statistical framework for assessing pharmacological response and biomarkers using uncertainty estimates

Wang et al. eLife, 2020

6. Why do pathway methods work better than they should?

Szalai FEBS letters, 2020

7. Decoding myofibroblast origins in human kidney fibrosis

Kuppe Nature, 2020

8. Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis

Mohs J Hepatology, 2020

9. The tissue proteome in the multi-omic landscape of kidney disease

Rinschen Nature Rev Nephrology, 2020

10. Gene selection for optimal prediction of cell position in tissues from single-cell transcriptomics data

Tanevski J Life Science Alliance, 2020

11. Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease

Sellmayr J Am Soc Nephrol, 2020

12. Inferring clonal composition from multiple tumor biopsies

Manica npj sys bio , 2020

13. BIAS: Transparent reporting of biomedical image analysis challenges

Maier-Hein Med Image Anal, 2020

14. Big Data Approaches in Heart Failure Research

Lanzer Current Heart Failure Reports, 2020

15. The Global Phosphorylation Landscape of SARS-CoV-2 Infection

Bouhaddou Cell, 2020

16. Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN

Gleitz H Blood, 2020

17. Community Assessment of the predictability of cancer protein and phosphoprotein levels from genomics and transcriptomics

Yang M Cell Systems, 2020

18. The Minimum Information about a Molecular Interaction Causal Statement (MI2CAST)

Touré V Bioinformatics, 2020

19. Converting networks to predictive logic models from perturbation signalling data with CellNOpt

Gjerga E Bioinformatics, 2020

20. Stratification and prediction of drug synergy based on target functional similarity

Yang M npj Systems Biology and Applications, 2020

21. CELLector: Genomics Guided Selection of Cancer in vitro Models

Najgebauer H Cell Systems, 2020

22. Setting the basis of best practices and standards for curation and annotation of logical models in biology—highlights of the [BC]2 2019 CoLoMoTo/SysMod Workshop

Niarakis A Briefings in Bioinformatics, 2020

23. Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

Eduati F Molecular systems biology, 2020

24. Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data

Holland CH Genome Biology, 2020

25. Dysregulated mesenchymal PDGFR-β drives kidney fibrosis

Buhl E EMBO Mol Med, 2020